Endocrine Abstracts

Introduction: Glitazones’ admisitration has been proved to affect EPCs in peripheral circulation in endothelial function and inflammatory process. The purpose of this study was to further investigate if the administration of pioglitazone in diabetics can modify the number of EPCs in the peripheral blood and alter the inflammatory state and endothelial function of these patients.Methods: Twenty five diabetic patients were recruited and pioglitazone w...

Introduction: Endothelial progenitor cells (EPCs) seems to be reduced in patients with diabetes mellitus, however it is unknown whether treatment with ACE-I may modify the number of EPCs. Therefore, the purpose of this study was to investigate if the administration of perindopril in diabetic patients with and without coronary artery disease can modify the number of circulating EPCs and alter their inflammatory state and endothelial function.Methods: Twen...